Group Members

Jamie_Blundell_10:2015.jpg

Jamie Blundell, group leader (2017 - present). [CV][Twitter][SCHOLAR]  

Jamie trained as a theoretical physicist at the Cavendish laboratory, University of Cambridge with Eugene Terentjev studying the statistical physics of polymers. He moved to Stanford University in 2012 as a postdoctoral scholar working on the dynamics of clonal evolution with Daniel Fisher, Sasha Levy, Dmitri Petrov and Gavin Sherlock. He joined the Cambridge Cancer Centre Early Detection program in July 2017. His research interests lie in quantitatively understanding somatic evolution in human tissues and using this understanding to detect cancer earlier.      


Caroline watson, clinical phd student (2017 - present)

Caroline qualified in medicine from the University of Oxford in 2010 and started training as a Haematology Specialist Registrar in Oxford in 2014.  Since October 2017 she is a CRUK funded clinical PhD student working on tracking clonal evolution during haematopoiesis. Her project involves generating and analysing ultra-deep sequencing data from longitudinal bloods taken over decade-long timescales in healthy individuals and those who develop Acute Myeloid Leukemia. She is also a widely published scientific illustrator.

Read more about Caroline's project


Gladys.jpeg

Gladys poon, phd student (2018 - present)

Gladys received her M.Sci and B.A. in Natural Sciences (Physics) at the University of Cambridge in 2018 and is continuing as a PhD student in the lab. Interested in the underlying mathematics of cancer progression, she will explore mathematical models of mutation dynamics in pre-cancerous tissues and the emergence of multiple-mutant clones as drivers of cancer progression.

Read more about Gladys’ project


jinqi.jpg

Jinqi Fu, postdoc (2018 - present)

Jinqi received her BSc in Veterinary Medicine from Qingdao Agricultural University and then moved to China’s CDC to complete her MSc on developing a universal vaccine against influenza A virus. She then obtained her PhD from the Department of Veterinary Medicine, University of Cambridge where she worked on developing a novel DNA barcoding system to investigate transmission dynamics of influenza A viruses among pig populations. She joined the Blundell lab in October 2018 and is working on (i) building a novel in-situ DNA barcoding technology, and, (ii) on using longitudinal TCR repertoire profiling as a possible early cancer detection tool.

Read more about Jinqi’s projects


Cordova%2C+Jonathon.jpg

jonathon cordova, masters student (2018 - present)

Jonathon graduated from the University of New Mexico in May of 2018 with a BS in Biochemistry. He is particularly interested in cancer biology and is a part of the MPhil program in medical science at the University of Cambridge. His project involves identifying and sequencing regulatory regions that are important for haematopoiesis in samples of longitudinal bloods in order to search for possible “regulatory clonal haematopoiesis”.

Read more about Jonathon’s project


Adriana.jpg

adriana fonseca, phd rotation student (2018 - present)

Adriana graduated with an MSci in Genetics from the University of Glasgow in 2018. She is on the CRUK Cambridge centre MRes+PhD programme in cancer biology and will be working on in-situ lineage tracking with inducible DNA barcodes. She is broadly interested in epigenetics.

Read more about Adriana’s project


Past group members

FullSizeRender[1].jpg

Emma Wagner, Research assistant (2017 - present)

Emma received her BSc in Physiology from the University of Aberdeen in 2013 and recently journeyed to Stockholm, Sweden to complete her MSc in Biomedicine at the Karolinska Institute in June 2017. She was a research assistant in the lab from 2017-2018 working on in-situ lineage tracking. In October 2018 Emma started a PhD in the Department of Pathology, University of Cambridge.


Matt_Photo.png

Matt Bradley, Masters project (PArt III)

Matt graduated from the four-year NST+MPhys course at the University of Cambridge in 2018. He was a part III masters project student in the lab working on developing simple mathematical models of mutation acquisition in cancer to figure out how much positive selection is likely acting on pre-cancerous clones before they progress to malignancy. Matt started a PhD in high energy physics at Imperial College London in October 2018.


Maria Tang, Post masters placement student (summer 2017)

Maria is graduating from the four-year Mathematics MMath at the University of Cambridge in 2017, with interests in mathematical and statistical modelling. Having found biology to contain many interesting and worthwhile quantitative problems, Maria worked on analyzing deep sequencing data sets and coming up with new ways to quantity genetic diversity from these. Maria is now doing a PhD in the Department of Applied Mathematics and Theoretical Physics, University of Cambridge looking at the mathematics of epidemics.


Collaborators

Doug Easton

Professor, Director Centre for Cancer Genetic Epidemiology, University of Cambridge

Sasha levy

Assistant Professor, Stony Brook University, SUNY

Daniel Fisher

Professor, Applied Physics, Stanford

Todd Druley

Associate Professor, Genetics and Developmental Biology, Washington University in St Louis

Usha menon

Professor of Gynaecological Cancer, UCL, London