The Evolutionary Dynamics and Fitness Landscape of Clonal Haematopoiesis

C. J Watson, A. Papula, Y. P. G. Poon, W. H. Wong, A. L. Young, T. E. Druley, D. S. Fisher, J. R Blundell

bioRxiv preprint


the dynamics of genetic diversity during the early stages of clonal evolution

J. R. Blundell, K. Schwartz, D. Francois, D. S. Fisher, G. Sherlock and S. F. Levy 

Nature Ecology & Evolution, 3, p293–301 (2019)

A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions

U. Schlecht*, Z. Liu*, J. R. Blundell, R. P. St. Onge, S. F. Levy. *Equal contribution

Nature Communications 8, 15586 (2017)

Development of a Comprehensive Genotype-to-Fitness Map of Adaptation-Driving Mutations in Yeast

S. Venkataram*, B. Dunn*, Y. Li, A. Argawala, J. Chang, E. Ebel, K. Geiler-Samerotte, L. Herrisant, J. R. Blundell, S. F. Levy, D. S. Fisher, G. Sherlock, D.A. Petrov. *Equal contribution

Cell  166, 1585-1596 (2016)


The obstruction of adaptation in diploids by recessive deleterious alleles

Z.J. Assaf, D.A. Petrov*, J. R. Blundell*. *Equal contribution 

PNAS 112(20), 2658-2666 (2015)


Quantitative evolutionary dynamics using high-resolution lineage tracking

S. F. Levy*, J. R. Blundell*, S. Venkataram, D. A. Petrov, D. S. Fisher and G. Sherlock. *Equal contribution 

Nature 519 181-186 (2015)