bioRxiv

The Evolutionary Dynamics and Fitness Landscape of Clonal Haematopoiesis

C. J Watson, A. Papula, Y. P. G. Poon, W. H. Wong, A. L. Young, T. E. Druley, D. S. Fisher, J. R Blundell

bioRxiv preprint


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the dynamics of genetic diversity during the early stages of clonal evolution

J. R. Blundell, K. Schwartz, D. Francois, D. S. Fisher, G. Sherlock and S. F. Levy 

Nature Ecology & Evolution, 3, p293–301 (2019)


A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions

U. Schlecht*, Z. Liu*, J. R. Blundell, R. P. St. Onge, S. F. Levy. *Equal contribution

Nature Communications 8, 15586 (2017)


Development of a Comprehensive Genotype-to-Fitness Map of Adaptation-Driving Mutations in Yeast

S. Venkataram*, B. Dunn*, Y. Li, A. Argawala, J. Chang, E. Ebel, K. Geiler-Samerotte, L. Herrisant, J. R. Blundell, S. F. Levy, D. S. Fisher, G. Sherlock, D.A. Petrov. *Equal contribution

Cell  166, 1585-1596 (2016)


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The obstruction of adaptation in diploids by recessive deleterious alleles

Z.J. Assaf, D.A. Petrov*, J. R. Blundell*. *Equal contribution 

PNAS 112(20), 2658-2666 (2015)


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Quantitative evolutionary dynamics using high-resolution lineage tracking

S. F. Levy*, J. R. Blundell*, S. Venkataram, D. A. Petrov, D. S. Fisher and G. Sherlock. *Equal contribution 

Nature 519 181-186 (2015)


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